Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035644 | 0.82 | HPGD (0.63) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL8630307 | 0.81 | HPGD (0.55) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL29149152 | 0.80 | CYP19A1 (0.61) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL15899626 | 0.78 | CYP3A4 (0.56) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL15360894 | 0.78 | VKORC1 (0.57) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL10800023 | 0.75 | HPGD (0.55) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL10800581 | 0.74 | HPGD (0.53) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL7141873 | 0.73 | CYP3A4 (0.61) | HPGDSMN1; SMN2NPC1RAB9ACYP3A4 | |
| SCHEMBL3205778 | 0.73 | HPGD (0.67) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 | |
| SCHEMBL312255 | 0.73 | AKR1C3 (1.00) | AKR1C3AKR1C2AKR1C1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | claimed |
| CN-119258055-A | Composition for inhibiting oral pathogenic bacteria and application thereof | 大连医科大学附属第二医院 | 2025-01-07 | — | — | CN | disclosed |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | UNIGEN, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| CN-112851615-B | Preparation of isopentenyl flavone and application of isopentenyl flavone as medicine for treating cervical cancer | 厦门大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112851615-B | Preparation of isopentenyl flavone and application of isopentenyl flavone as medicine for treating cervical cancer | 厦门大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-112552309-B | Psoralen benzene sulfonate derivative and application thereof | 中国科学院新疆理化技术研究所 | 2023-03-14 | — | — | CN | disclosed |
| CN-115650942-A | Method for extracting, separating and purifying 8-isopentenyl naringenin from hops | 长沙市惠瑞生物科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-113004353-B | Cyclocarya paliurus extract and application thereof | 中南大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-113150048-B | Cyclocarya paliurus extract and application thereof in resisting rheumatoid arthritis | 中南大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114796194-A | Application of DA adduct derived from Morus plant in preparation of beta-G inhibitor | 澳门大学 | 2022-07-29 | — | — | CN | disclosed |
| EP-1453827-A4 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | UNIV SINGAPORE (SG) | 2005-02-23 | — | — | EP | disclosed |
| EP-1453827-A1 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-09-08 | — | — | EP | disclosed |
| US-6750248-B2 | FLAVONE ANALOGS MODULATE ESTROGEN RECEPTORS; USEFUL IN TREATING MENOPAUSE SYMPTOMS AND ESTROGEN-DEPENDENT CANCERS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2004-06-15 | — | — | US | disclosed |
| WO-2003040134-A9 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | UNIV SINGAPORE (SG) | 2004-03-25 | — | — | WO | disclosed |
| US-20030190375-A1 | Therapeutical use of sophora flavescens or sophora subprostrata extracts | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2003-10-09 | — | — | US | disclosed |
| US-20030180394-A1 | Extracts from sophora species, method for producing the same and their use | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 2003-09-25 | — | — | US | disclosed |
| US-20030170292-A1 | Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof | NATIONAL UNIVERSITY OF SINGAPORE | 2003-09-11 | — | — | US | disclosed |
| WO-2003040134-A1 | METHODS FOR PREPARING AN ESTROGENIC PREPARATION AND ISOLATED ESTROGENIC COMPOUNDS FROM A PLANT AND USES THEREOF | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2003-05-15 | — | — | WO | disclosed |
| WO-2002051426-A2 | COMPOSITIONS AND METHODS FOR TREATING SEXUAL DYSFUNCTION, ENHANCING SEXUAL FUNCTION, INCREASING TESTOSTERONE LEVELS, AND IMPROVING MUSCLE STRENGTH AND MASS | BRASWELL A GLENN (US) | 2002-07-04 | — | — | WO | disclosed |
| US-6071883-A | ADMINISTERING FLAVONE DERIVATIVE AS AN IMMUNOSUPPRESSANT TO THE RECIPIENT IN NEED OF A GRAFT REJECTION PREVENTION OR SUPPRESSION AFTER ALLOGRAFT ORGAN TRANSPLANT | CHEN HUIFANG (CA) | 2000-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030190375-A1 | Therapeutical use of sophora flavescens or sophora subprostrata extracts | SHBG, CYP19A1, HSD17B11 | AKR1C3 238/4885AKR1C2 411/4885AKR1C1 465/4885 |
| US-20030170292-A1 | Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof | ESR1, ESR2, GPER1 | AKR1C3 719/4885AKR1C2 547/4885AKR1C1 782/4885 |
| US-20030180394-A1 | Extracts from sophora species, method for producing the same and their use | CYP19A1, SHBG, CYP17A1 | AKR1C3 1730/4885AKR1C2 1821/4885AKR1C1 2075/4885 |
| US-20230190852-A1 | COMPOSITIONS AND METHODS FOR JOINT HEALTH | PTGES, PTGES3, PTGES2 | AKR1C3 2167/4885AKR1C2 2748/4885AKR1C1 2973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.