Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PPOX | P50336 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31009328 | 0.88 | LMNA (0.47) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL24749622 | 0.88 | LMNA (0.47) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL31009354 | 0.84 | PTGES (0.54) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL13881915 | 0.82 | LMNA (0.55) | MAPTMEN1KMT2ATTRPPOX | |
| SCHEMBL1340465 | 0.82 | POLB (0.56) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL6748915 | 0.78 | MAPT (0.47) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL4607970 | 0.78 | MAPT (0.47) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL4348623 | 0.77 | MAPT (0.51) | PTGESMAPTMEN1KMT2ATTR | |
| SCHEMBL13220963 | 0.76 | MAPT (0.62) | MAPTMEN1KMT2ATTRPPOX | |
| SCHEMBL11183119 | 0.76 | KDM4E (0.48) | PTGESMAPTMEN1KMT2ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |