SCHEMBL2915

SCHEMBL2915

CCCN([C]=O)CCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270410 0.89 CA1 (0.34)
SCHEMBL96462 0.88
SCHEMBL271368 0.87 DNM1 (0.40)
SCHEMBL1998903 0.87
SCHEMBL9661735 0.84 DNM1 (0.44)
SCHEMBL9660183 0.84 DNM1 (0.44)
SCHEMBL22395234 0.84 DNM1 (0.44)
SCHEMBL9661146 0.84 DNM1 (0.44)
SCHEMBL9658807 0.84 DNM1 (0.44)
SCHEMBL9660664 0.84 DNM1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3955 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200325156-A1 HETEROARYL AMIDE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF RUI JIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE (CN) 2020-10-15 US claimed
EP-3705481-A1 HETEROARYL AMIDE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITIONS THEREOF, AND APPLICATIONS THEREOF Rui Jin Hospital Affiliated To Shanghai Jiao Tong University School of Medicine (CN) 2020-09-09 EP claimed
WO-2019196111-A1 ANTI-TUMOR MULTIDRUG RESISTANCE OF HETEROARYL AMIDE COMPOUND, USE IN TREATMENT OF CANCERS AND PROTEIN-DRUG MOLECULAR COMPLEX 上海交通大学医学院附属瑞金医院 2019-10-17 WO claimed
EP-3106459-B1 PYRROLE-SUBSTITUTED INDOLONE DERIVATIVE, PREPARATION METHOD THEREFOR, COMPOSITION COMPRISING SAME AND USE THEREOF SHIJIAZHUANG YILING PHARMACEUTICAL CO LTD (CN) 2018-07-04 EP claimed
US-9556154-B2 Pyrrole-substituted indolone derivative, preparation method therefor, composition comprising same and use thereof SHIJIAZHUANG YILING PHARMACEUTICAL CO. LTD. (CN) 2017-01-31 US claimed
EP-3106459-A1 PYRROLE-SUBSTITUTED INDOLONE DERIVATIVE, PREPARATION METHOD THEREFOR, COMPOSITION COMPRISING SAME AND USE THEREOF Shijiazhuang Yiling Pharmaceutical Co., Ltd. (CN) 2016-12-21 EP claimed
US-20160347740-A1 PYRROLE-SUBSTITUTED INDOLONE DERIVATIVE, PREPARATION METHOD THEREFOR, COMPOSITION COMPRISING SAME AND USE THEREOF SHIJIAZHUANG YILING PHARMACEUTICAL CO., LTD. (CN) 2016-12-01 US claimed
EP-1480944-B1 SUBSTITUTED ARYL KETONES BAYER IP GMBH (DE) 2016-08-10 EP claimed
US-9073956-B1 Dihydro-1H-phosphole 1-oxide derivatives and preparation method thereof KNU-INDUSTRY COOPERATION FOUNDATION (KR) 2015-07-07 US claimed
EP-1790639-B1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS CXCR4-ANTAGONISTS ONO PHARMACEUTICAL CO (JP) 2014-03-26 EP claimed
EP-0299683-A2 Heterocyclic olefinic compounds and their use as aromatase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-01-18 EP claimed
EP-0281283-A1 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-09-07 EP claimed
EP-0277537-A1 1-Aminomethyl-3-aryl-4-cyano-pyrrole BAYER AG (DE) 1988-08-10 EP claimed
EP-0264021-A2 0-Aryl-N'-(triazin-2-yl)-isourea BAYER AG (DE) 1988-04-20 EP claimed
US-4650868-A 7-deazapurine derivatives useful as antitumor agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1987-03-17 US claimed
EP-0064199-B1 NOVEL SECALONIC ACID DERIVATIVES AND METHOD FOR PREPARING THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-08-21 EP claimed
EP-0064199-A1 Novel secalonic acid derivatives and method for preparing thereof Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-11-10 EP claimed
US-4315855-A Monoazo disperse dyes containing a nitrophenyl group and a homophthalimide group BASF AKTIENGESELLSCHAFT (DE) 1982-02-16 US claimed
US-4268510-A DEMETHANIZATION, METABOLISM, RUMEN IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-05-19 US claimed
EP-0010348-A1 Heterocyclic trichloromethyl derivatives, process for their preparation and their use IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-04-30 EP claimed