Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 2/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15446373 | 0.86 | KMO (0.42) | KMO | |
| SCHEMBL25147466 | 0.78 | PIK3CD (0.41) | KDM5BKMOPIK3CDPIK3CACHRM4 | |
| SCHEMBL2595624 | 0.78 | KMO (0.40) | KDM5BKMOPIK3CDPIK3CACHRM4 | |
| SCHEMBL23025135 | 0.78 | RET (0.38) | KDM5BKMOPIK3CDPIK3CACSF1R | |
| SCHEMBL25147385 | 0.74 | KDM5B (0.35) | KDM5BKMOPIK3CDPIK3CACHRM4 | |
| SCHEMBL16692772 | 0.73 | PIK3CD (0.43) | KDM5BPIK3CDPIK3CAMAPK1MAP3K12 | |
| SCHEMBL29979598 | 0.73 | PIK3CD (0.43) | KDM5BPIK3CDPIK3CAMAPK1MAP3K12 | |
| SCHEMBL31705056 | 0.73 | KMO (0.71) | KMO | |
| Lithium Ion SCHEMBL31704699 | 0.70 | KMO (0.51) | KDM5BKMOPIK3CDPIK3CADAO | |
| SCHEMBL16441792 | 0.70 | KMO (0.48) | KMORETLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |