Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | CASP7 | P55210 | 4/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | STAT3 | P40763 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303326 | 0.80 | KDM4E (0.61) | KMT2AMEN1GLACYP3A4KDM4E | |
| SCHEMBL13490121 | 0.78 | KDM4E (0.44) | KMT2AMEN1GLACYP3A4KDM4E | |
| SCHEMBL23376618 | 0.76 | CYP3A4 (0.47) | KMT2AMEN1GLACYP3A4KDM4E | |
| 4-Hydroxy-6-Methylpyran-2-One SCHEMBL22656780 | 0.74 | CYP3A4 (0.87) | KMT2AMEN1GLACYP3A4KDM4E | |
| SCHEMBL13872419 | 0.72 | STAT3 (0.47) | KMT2AMEN1GLACYP3A4KDM4E | |
| 4-Hydroxy-6-Methylpyran-2-One SCHEMBL320025 | 0.70 | — | — | |
| SCHEMBL30302271 | 0.69 | CYP3A4 (0.48) | KMT2AMEN1GLACYP3A4KDM4E | |
| SCHEMBL23376562 | 0.69 | CYP3A4 (0.44) | KMT2AMEN1GLACYP3A4KDM4E | |
| SCHEMBL11619492 | 0.69 | — | — | |
| SCHEMBL15349674 | 0.68 | ALDH1A1 (0.57) | KMT2AMEN1GLACYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143062-B | 4-Hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-117143062-A | 3-substituted 4-hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2023-12-01 | — | — | CN | disclosed |