Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | CBS | P35520 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150883 | 0.87 | ELANE (0.64) | ELANEACHESGMS1SGMS2KMT2A | |
| SCHEMBL29150901 | 0.85 | NFKB1 (0.59) | ELANEKMT2AMEN1SLC5A1SLC5A2 | |
| SCHEMBL29150893 | 0.82 | ELANE (0.68) | ELANEACHESGMS1SGMS2SLC5A1 | |
| SCHEMBL29150872 | 0.82 | SLC5A1 (0.65) | ELANEKMT2AMEN1SLC5A1SLC5A2 | |
| SCHEMBL27035935 | 0.81 | ELANE (0.88) | ELANEKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL27035891 | 0.81 | ELANE (0.88) | ELANEKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL27035967 | 0.81 | ELANE (0.88) | ELANEKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL27035914 | 0.81 | ELANE (0.88) | ELANEKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL27035911 | 0.81 | ELANE (0.88) | ELANEKMT2AMEN1USP2ALDH1A1 | |
| SCHEMBL29150882 | 0.80 | ELANE (0.56) | ELANEKMT2AMEN1SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143062-B | 4-Hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-117143062-A | 3-substituted 4-hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2023-12-01 | — | — | CN | disclosed |