Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.64 |
| ▸ | CBS | P35520 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | SGMS1 | Q86VZ5 | 2/20 | 0.51 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.50 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29150893 | 0.95 | ELANE (0.68) | ELANECBSALDH1A1ACHESGMS1 | |
| SCHEMBL458844 | 0.92 | GAA (0.60) | ELANECBSALDH1A1GAAMAPT | |
| SCHEMBL29150899 | 0.87 | ELANE (0.61) | ELANECBSALDH1A1ACHESGMS1 | |
| SCHEMBL29150901 | 0.85 | NFKB1 (0.59) | ELANEALDH1A1MAPTSLC5A1SLC5A2 | |
| SCHEMBL27035914 | 0.83 | ELANE (0.88) | ELANEALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL27035967 | 0.83 | ELANE (0.88) | ELANEALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL27035911 | 0.83 | ELANE (0.88) | ELANEALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL27035891 | 0.83 | ELANE (0.88) | ELANEALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL27035935 | 0.83 | ELANE (0.88) | ELANEALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL29150872 | 0.81 | SLC5A1 (0.65) | ELANEALDH1A1GAAMAPTSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117143062-B | 4-Hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-117143062-A | 3-substituted 4-hydroxy-2-pyrone compound, preparation method and application | 西北农林科技大学 | 2023-12-01 | — | — | CN | disclosed |