SCHEMBL29152142

SCHEMBL29152142

Cc1ccc(-c2c3ccccc3c(C#N)c3ccccc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 4/20 0.56
PDE1C Q14123 2/20 0.56
ADORA1 P30542 4/20 0.46
ADORA2A P29274 3/20 0.46
HPGD P15428 4/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
ACHE P22303 1/20 0.45
ALDH1A1 P00352 7/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ADORA2B P29275 1/20 0.44
KDM4E B2RXH2 6/20 0.43
GAA P10253 3/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30662428 0.87 PDE9A (0.44) PDE9APDE1CADORA1ADORA2AHPGD
SCHEMBL12245636 0.85 ALDH1A1 (0.61) PDE9APDE1CADORA1ADORA2AHPGD
SCHEMBL29152127 0.84 ALDH1A1 (0.54) PDE9AADORA1ADORA2AHPGDACHE
SCHEMBL30742831 0.83 ACHE (0.57) PDE9APDE1CADORA2AHPGDACHE
SCHEMBL3477351 0.83 ACHE (0.57) PDE9APDE1CADORA2AHPGDACHE
SCHEMBL29152134 0.82 AR (0.46) PDE9APDE1CALDH1A1MAPTMEN1
SCHEMBL29152140 0.81 ADORA2A (0.46) PDE9APDE1CADORA1ADORA2AHPGD
SCHEMBL29152120 0.81 USP2 (0.44) PDE9APDE1CADORA1ADORA2AHPGD
SCHEMBL29152145 0.81 ADORA1 (0.46) PDE9APDE1CADORA1ADORA2AHPGD
SCHEMBL29152143 0.80 ADORA1 (0.48) PDE9APDE1CADORA1ADORA2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164478-A Method for preparing anthracycline derivative 苏州大学 2023-12-05 CN disclosed