Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.50 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.50 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.50 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15547888 | 0.91 | POLM (0.55) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL15548023 | 0.91 | POLM (0.55) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL15548447 | 0.89 | POLM (0.53) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL11277533 | 0.86 | KMT2A (0.46) | KMT2AMEN1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15558766 | 0.84 | KMT2A (0.56) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL8088316 | 0.83 | KMT2A (0.57) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL9322247 | 0.83 | KMT2A (0.57) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL27508353 | 0.83 | KMT2A (0.57) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL17138174 | 0.82 | POLM (0.62) | POLMPOLKPOLLPOLHKMT2A | |
| SCHEMBL9177728 | 0.82 | KMT2A (0.58) | POLMPOLKPOLLPOLHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377468-A | 2, 6-dichlorophenyl ester compound and application thereof | 融合制药公司 | 2024-01-09 | — | — | CN | disclosed |