Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | F2R | P25116 | 2/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450909 | 0.89 | SMN1; SMN2 (0.42) | KMT2ABCL9CTNNB1ALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28401106 | 0.87 | ABCB11 (0.40) | KMT2ABCL9CTNNB1HTTALOX15 | |
| SCHEMBL29152244 | 0.86 | POLM (0.50) | KMT2AHTTALOX15ALDH1A1KDM4E | |
| SCHEMBL2898218 | 0.85 | KMT2A (0.48) | KMT2AHTTALOX15ALDH1A1NLRP3 | |
| SCHEMBL24636722 | 0.83 | KMT2A (0.47) | KMT2AHTTALDH1A1NLRP3PTPN7 | |
| SCHEMBL29372461 | 0.82 | CNR2 (0.38) | KMT2ABCL9CTNNB1HTTALDH1A1 | |
| SCHEMBL9716061 | 0.81 | KMT2A (0.46) | KMT2AHTTALDH1A1NLRP3PTPN7 | |
| SCHEMBL4573844 | 0.81 | KMT2A (0.45) | KMT2ABCL9CTNNB1HTTALOX15 | |
| SCHEMBL15558766 | 0.80 | KMT2A (0.56) | KMT2AHTTALOX15ALDH1A1KDM4E | |
| SCHEMBL7496459 | 0.80 | MAPT (0.47) | HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349378-A | Compounds useful as pesticides | FBC LIMITED (GB) | 1982-09-14 | — | — | US | disclosed |
| US-4185992-A | Imidazole derivatives | MAY & BAKER LIMITED (GB) | 1980-01-29 | — | — | US | disclosed |
| EP-0002881-A1 | 5-Isoxazolylurea derivatives, their preparation, their use and compositions containing them | FISONS plc (GB) | 1979-07-11 | — | — | EP | disclosed |