Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2916365 | 0.87 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL2915746 | 0.86 | CRBN (0.37) | CRBNRIPK2ACVR1NOD2CYP3A4 | |
| SCHEMBL2915572 | 0.83 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL1530691 | 0.82 | CRBN (0.34) | CRBNRIPK2ACVR1NOD2CYP3A4 | |
| SCHEMBL2908256 | 0.82 | CRBN (0.42) | CRBNACVR1CYP3A4 | |
| SCHEMBL2913987 | 0.81 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL2913169 | 0.81 | CRBN (0.40) | CRBNCYP3A4 | |
| SCHEMBL2913326 | 0.81 | CRBN (0.38) | CRBNACVR1CYP3A4 | |
| SCHEMBL2913397 | 0.81 | CRBN (0.33) | CRBN | |
| SCHEMBL2914780 | 0.81 | CRBN (0.32) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |