Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194858 | 0.94 | MAPK13 (0.54) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL2091239 | 0.87 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL6231072 | 0.86 | ESR2 (0.53) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL19627030 | 0.84 | MAPK13 (0.60) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL11751183 | 0.83 | KDM4E (0.55) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL11755271 | 0.83 | ALDH1A1 (0.55) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL11748988 | 0.83 | ALDH1A1 (0.55) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL11751436 | 0.83 | KDM4E (0.55) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL13772726 | 0.81 | MAPK13 (0.57) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL13772755 | 0.81 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-B | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |