Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.69 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.69 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.69 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194860 | 0.93 | MAPK13 (0.57) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL2091239 | 0.89 | MAPK13 (0.83) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL29154645 | 0.83 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL13772755 | 0.83 | MAPK13 (0.69) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL6516453 | 0.82 | PTGS2 (0.48) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL6516224 | 0.82 | PTGS2 (0.52) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL1387446 | 0.81 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL14660408 | 0.81 | NR1H4 (0.53) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL29154641 | 0.81 | MAPK13 (0.65) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL6513045 | 0.80 | PTGS2 (0.77) | MAPK13MAPK12MAPK11MAPK14PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510430-B | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-10-25 | — | — | CN | disclosed |
| CN-117510430-A | Oxazole compound and synthetic method and application thereof | 南昌大学 | 2024-02-06 | — | — | CN | disclosed |