Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | IDE | P14735 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HLCS | P50747 | 6/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25982120 | 0.93 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL19803917 | 0.87 | TDP1 (0.72) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL26345911 | 0.86 | PRSS1 (0.73) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL1328284 | 0.85 | TDP1 (0.58) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL15281582 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12965054 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL26709365 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL15987009 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL12043072 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL26702432 | 0.85 | F2 (0.76) | TDP1PKMMEN1ABL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529711-A | Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds | UNIV GEORGIA | 2015-04-22 | — | — | CN | disclosed |
| CN-101925366-B | Alkynes and methods of reacting alkynes with 1, 3-dipole-functional compounds | UNIV GEORGIA | 2015-02-04 | — | — | CN | disclosed |
| EP-2222341-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | University Of Georgia Research Foundation, Inc. (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009067663-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2009-05-28 | — | — | WO | disclosed |
| EP-0944820-A4 | MULTI-ARRAY, MULTI-SPECIFIC ELECTROCHEMILUMINESCENT TESTING | MESO SCALE TECHNOLOGIES LLC (US) | 2000-04-26 | — | — | EP | disclosed |
| EP-0944820-A1 | MULTI-ARRAY, MULTI-SPECIFIC ELECTROCHEMILUMINESCENT TESTING | Meso Scale Technologies, LLC. (US) | 1999-09-29 | — | — | EP | disclosed |
| WO-1998012539-A1 | MULTI-ARRAY, MULTI-SPECIFIC ELECTROCHEMILUMINESCENCE TESTING | MESO SCALE TECHNOLOGIES, LLC (US) | 1998-03-26 | — | — | WO | disclosed |