Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | HLCS | P50747 | 6/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | IDE | P14735 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479435 | 0.99 | TDP1 (0.59) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL5573517 | 0.95 | F2 (0.56) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL2915470 | 0.85 | TDP1 (0.63) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL25982120 | 0.83 | TDP1 (0.65) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL30958922 | 0.82 | TDP1 (0.58) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL12965054 | 0.82 | F2 (0.76) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL26709365 | 0.82 | F2 (0.76) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL15987009 | 0.82 | F2 (0.76) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL12043072 | 0.82 | F2 (0.76) | TDP1HLCSPKMMEN1ABL1 | |
| SCHEMBL15281582 | 0.82 | F2 (0.76) | TDP1HLCSPKMMEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6977138-B2 | Reactive polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-12-20 | — | — | US | claimed |
| EP-1476255-A2 | REACTIVE POLYMER COATINGS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-11-17 | — | — | EP | claimed |
| US-20030044546-A1 | Reactive polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-03-06 | — | — | US | claimed |
| WO-2003010354-A2 | REACTIVE POLYMER COATINGS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-02-06 | — | — | WO | claimed |
| US-11971419-B2 | Hydroxycholesterol immunoassay | ENZO LIFE SCIENCES, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| US-20220074941-A1 | HSP90 COMBINATION THERAPY | SLOAN KETTERING INST CANCER RES (US) | 2022-03-10 | — | — | US | disclosed |
| US-20210302445-A1 | HYDROXYCHOLESTEROL IMMUNOASSAY | ENZO LIFE SCIENCES, INC. (US) | 2021-09-30 | — | — | US | disclosed |
| EP-2479268-B1 | DISSOCIATION METHOD AND DISSOCIATION AGENT FOR AVIDIN AND BIOTINDERIVATIVES | JSR CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-3006514-B1 | INK COMPOSITION FOR INKJET PRINTING | FUND EURECAT (ES) | 2020-02-12 | — | — | EP | disclosed |
| US-10314882-B2 | Methods, uses and compositions of Tie2 agonists | Sunnybrook Research Institute | 2019-06-11 | — | — | US | disclosed |
| EP-2983695-B1 | METHODS, USES AND COMPOSITIONS OF TIE2 AGONISTS | SUNNYBROOK RES INST (CA) | 2019-05-29 | — | — | EP | disclosed |
| US-10197583-B2 | Hydroxycholesterol immunoassay | ENZO LIFE SCIENCES, INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20030059537-A1 | Microstamping activated polymer surfaces | DUKE UNIVERSITY | 2003-03-27 | — | — | US | disclosed |
| US-20030044546-A1 | Reactive polymer coatings | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2003-03-06 | — | — | US | disclosed |
| WO-2003010354-A2 | REACTIVE POLYMER COATINGS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-02-06 | — | — | WO | disclosed |
| EP-1269189-A2 | MICROSTAMPING ACTIVATED POLYMER SURFACES | DUKE UNIVERSITY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002094456-A1 | FABRICATION OF MICRODEVICES FOR SEPARATION OF BIOMOLECULES IN AN ELECTRICAL FIELD | LAHANN JOERG (US) | 2002-11-28 | — | — | WO | disclosed |
| WO-2002094454-A1 | FABRICATION OF MICRODEVICES FOR PARALLEL ANALYSIS OF BIOMOLECULES | LAHANN JOERG (US) | 2002-11-28 | — | — | WO | disclosed |
| US-6444254-B1 | ACTIVATION; BONDING | DUKE UNIVERSITY | 2002-09-03 | — | — | US | disclosed |
| WO-2001067104-A2 | MICROSTAMPING ACTIVATED POLYMER SURFACES | DUKE UNIVERSITY (US) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220074941-A1 | HSP90 COMBINATION THERAPY | HSP90AB1, HSP90AB2P, HSP90B1 | TDP1 2249/4885HLCS 892/4885PKM 3630/4885 |
| US-10197583-B2 | Hydroxycholesterol immunoassay | CYP46A1, CYP27A1, DHCR7 | TDP1 1599/4885HLCS 69/4885PKM 4095/4885 |
| US-20210302445-A1 | HYDROXYCHOLESTEROL IMMUNOASSAY | CYP46A1, CYP27A1, DHCR7 | TDP1 4356/4885HLCS 80/4885PKM 4667/4885 |
| US-11971419-B2 | Hydroxycholesterol immunoassay | CYP46A1, CYP27A1, DHCR7 | TDP1 4356/4885HLCS 80/4885PKM 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.