Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL30648131 | 0.79 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL15145693 | 0.78 | HTR5A (0.39) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14433403 | 0.78 | HTR5A (0.39) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8937088 | 0.78 | LMNA (0.46) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30681298 | 0.78 | LMNA (0.46) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29529402 | 0.78 | LMNA (0.46) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL13496703 | 0.74 | HTR5A (0.36) | HTR5ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7144285 | 0.72 | GAA (0.42) | HTR5AACHEMAPTKMT2A | |
| SCHEMBL1760655 | 0.72 | GAA (0.42) | HTR5AMAPT | |
| SCHEMBL14081694 | 0.69 | GAA (0.40) | ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108957-B | Synthesis method of chiral 2-phenylpyrrolidine | 深圳博瑞医药科技有限公司 | 2023-12-29 | — | — | CN | disclosed |