Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908752 | 0.82 | AKR1B1 (0.47) | KDM4EGAAFFAR1PTGDR2HTT | |
| SCHEMBL7412851 | 0.82 | FFAR1 (0.47) | KDM4EALDH1A1GAAFFAR1FFAR4 | |
| SCHEMBL6072554 | 0.81 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAHTTSLC6A2 | |
| SCHEMBL11213637 | 0.81 | FFAR1 (0.45) | FFAR1PTGDR2HTTFFAR4CTBP2 | |
| SCHEMBL1026069 | 0.80 | CYP2A6 (0.48) | KDM4EALDH1A1GAASLC6A2SLC6A4 | |
| SCHEMBL3017976 | 0.79 | MEN1 (0.41) | FFAR1PTGDR2HTTFFAR4CTBP2 | |
| SCHEMBL30349567 | 0.79 | ALDH1A1 (0.50) | ALDH1A1FFAR1PTGDR2HTT | |
| SCHEMBL20844673 | 0.79 | RXRA (0.48) | KDM4EGAAFFAR1PTGDR2HTT | |
| SCHEMBL29810587 | 0.79 | FFAR1 (0.53) | FFAR1PTGDR2FFAR4RXRARXRG | |
| SCHEMBL14660970 | 0.79 | ALDH1A1 (0.50) | ALDH1A1FFAR1PTGDR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117024410-A | Airotinib intermediate and preparation method thereof | 上海药坦药物研究开发有限公司 | 2023-11-10 | — | — | CN | disclosed |