SCHEMBL291555

SCHEMBL291555

C=C(Cl)C(=C)c1ccccc1Nc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.53
MAPT P10636 5/20 0.50
ALOX15 P16050 2/20 0.50
MEN1 O00255 4/20 0.44
KMT2A Q03164 4/20 0.44
KDM4E B2RXH2 2/20 0.44
GAA P10253 2/20 0.44
GLA P06280 1/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
SIRT2 Q8IXJ6 5/20 0.42
PTGS1 P23219 2/20 0.41
AKR1C3 P42330 2/20 0.41
AKR1C2 P52895 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL293103 0.81 MAPT (0.54) FABP4MAPTALOX15MEN1KMT2A
SCHEMBL530311 0.79 FABP4 (0.59) FABP4MAPTALOX15MEN1KMT2A
SCHEMBL28350435 0.77 MAPT (0.58) FABP4MAPTALOX15MEN1KMT2A
SCHEMBL11787978 0.77 FABP4 (0.67) FABP4MAPTALOX15MEN1KMT2A
SCHEMBL4888834 0.74 MAPT (0.54) FABP4MAPTALOX15MEN1KMT2A
SCHEMBL14269562 0.74 MAPT (0.54) FABP4MAPTALOX15MEN1KMT2A
Fenamic Acid SCHEMBL27781283 0.73 FABP4 (0.85) FABP4MAPTALOX15MEN1KMT2A
Fenamic Acid SCHEMBL25828 0.72 FABP4 (0.92) FABP4MAPTALOX15MEN1KMT2A
Fenamic Acid SCHEMBL29622832 0.72 FABP4 (0.92) FABP4MAPTALOX15MEN1KMT2A
Fenamic Acid SCHEMBL11800213 0.71 FABP4 (0.89) FABP4MAPTALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-3029099-B1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2018-04-04 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
EP-2799482-B1 Rubber composition and tire produced using same, and process of producing rubber composition BRIDGESTONE CORP (JP) 2017-03-29 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
US-20160168365-A1 PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2016-06-16 US disclosed
EP-3029099-A1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION Bridgestone Corporation (JP) 2016-06-08 EP disclosed
US-20070221310-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2007-09-27 US disclosed
EP-1834980-A1 MODIFIED NATURAL RUBBER MASTERBATCH AND METHOD FOR PRODUCTION THEREOF, AND RUBBER COMPOSITION AND TIRE Bridgestone Corporation (JP) 2007-09-19 EP disclosed
EP-1818186-A1 PNEUMATIC TIRE Bridgestone Corporation (JP) 2007-08-15 EP disclosed
US-20070010610-A1 Modified natural rubber or modified natural rubber latex, and rubber composition and pneumatic tire BRIDGESTONE CORPORATION (JP) 2007-01-11 US disclosed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP disclosed
US-20050182159-A1 Diene rubber-inorganic compound composite and process for producing the same JRS CORPORATION (JP) 2005-08-18 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed