SCHEMBL293103

SCHEMBL293103

C=C(C)C(=C)c1ccccc1Nc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
ALOX15 P16050 2/20 0.54
FABP4 P15090 1/20 0.53
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
SIRT2 Q8IXJ6 8/20 0.45
AKR1C3 P42330 2/20 0.45
AKR1C2 P52895 2/20 0.45
KDM4E B2RXH2 3/20 0.44
GAA P10253 2/20 0.44
GLA P06280 1/20 0.44
RECQL P46063 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PTGS1 P23219 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28350435 0.85 MAPT (0.58) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL291555 0.81 FABP4 (0.53) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL530311 0.79 FABP4 (0.59) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL13347968 0.79 MAOA (0.38) MAPTSIRT2KDM4EGAATDP1
SCHEMBL24934177 0.77 MAPT (0.58) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL30567367 0.77 MAPT (0.68) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL848485 0.77 MAPT (0.68) MAPTALOX15FABP4MEN1KMT2A
Fenamic Acid SCHEMBL27925717 0.76 FABP4 (0.82) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL14269562 0.74 MAPT (0.54) MAPTALOX15FABP4MEN1KMT2A
SCHEMBL4888834 0.74 MAPT (0.54) MAPTALOX15FABP4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851489-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT BRIDGESTONE CORPORATION (JP) 2021-07-21 EP disclosed
WO-2020054484-A1 MODIFIED MULTI-COMPONENT COPOLYMER, RUBBER COMPOSITION, RESIN COMPOSITION, TIRE AND RESIN PRODUCT 株式会社ブリヂストン 2020-03-19 WO disclosed
US-20180244808-A1 METHOD FOR PRODUCING MODIFIED DIENE-BASED RUBBER, RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2018-08-30 US disclosed
EP-3345933-A1 METHOD FOR PRODUCING MODIFIED DIENE RUBBER, RUBBER COMPOSITION, AND TIRE Bridgestone Corporation (JP) 2018-07-11 EP disclosed
EP-3029099-B1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORP (JP) 2018-04-04 EP disclosed
EP-2845869-B1 MODIFIED NATURAL RUBBER, METHOD FOR PRODUCING SAME, RUBBER COMPOSITION, AND TIRE BRIDGESTONE CORP (JP) 2018-01-17 EP disclosed
EP-2799482-B1 Rubber composition and tire produced using same, and process of producing rubber composition BRIDGESTONE CORP (JP) 2017-03-29 EP disclosed
US-9428619-B2 Interpolymers containing isobutylene and diene mer units BRIDGESTONE CORPORATION (JP) 2016-08-30 US disclosed
US-20160168365-A1 PROCESS OF PRODUCING RUBBER COMPOSITION BRIDGESTONE CORPORATION (JP) 2016-06-16 US disclosed
EP-3029099-A1 RUBBER COMPOSITION AND TIRE PRODUCED USING SAME, AND PROCESS OF PRODUCING RUBBER COMPOSITION Bridgestone Corporation (JP) 2016-06-08 EP disclosed
EP-1215226-B1 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR CORP (JP) 2006-06-07 EP disclosed
EP-1629021-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE Bridgestone Corporation (JP) 2006-03-01 EP disclosed
US-20050182159-A1 Diene rubber-inorganic compound composite and process for producing the same JRS CORPORATION (JP) 2005-08-18 US disclosed
EP-1500679-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2005-01-26 EP disclosed
WO-2004106397-A1 MODIFIED NATURAL RUBBER OR MODIFIED NATURAL RUBBER LATEX, AND RUBBER COMPOSITION AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2004-12-09 WO disclosed
US-6740704-B2 UNIFORM DISPERSION JSR CORPORATION (JP) 2004-05-25 US disclosed
US-20040030027-A1 Diene rubber/inorganic compound composite and method for producing the same and rubber composition BRIDGESTONE CORPORATION (JP) 2004-02-12 US disclosed
EP-1323775-A1 DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION JSR Corporation (JP) 2003-07-02 EP disclosed
US-20020111418-A1 Methods for producing diene-based rubber/inorganic compound complexes and rubber compositions containing the same JSR CORPORATION (JP) 2002-08-15 US disclosed
EP-1215226-A2 Diene-based rubber/inorganic compound complexes, methods for producing the same and rubber compositions containing the same JSR Corporation (JP) 2002-06-19 EP disclosed