Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 8/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909795 | 0.89 | NR1H4 (0.39) | CFTRNR1H4KDM4EMAPTPOLB | |
| SCHEMBL2913875 | 0.87 | F10 (0.37) | NR1H4KDM4EMAPTNPC1POLB | |
| SCHEMBL2913384 | 0.86 | NR1H4 (0.40) | CFTRNR1H4KDM4EMAPTNPC1 | |
| SCHEMBL2915054 | 0.86 | NR1H4 (0.40) | CFTRNR1H4KDM4EMAPTNPC1 | |
| SCHEMBL2913600 | 0.86 | NR1H4 (0.40) | NR1H4KDM4EMAPTPOLBF10 | |
| SCHEMBL2917122 | 0.84 | MAPT (0.42) | NR1H4MAPTNPC1RAB9AF10 | |
| SCHEMBL2907136 | 0.83 | NR1H4 (0.38) | CFTRNR1H4KDM4EMAPTNPC1 | |
| SCHEMBL2916146 | 0.83 | ALDH1A1 (0.38) | NR1H4MAPTNPC1RAB9AF10 | |
| SCHEMBL2915689 | 0.83 | F10 (0.39) | MAPTNPC1RAB9AF10SMN1; SMN2 | |
| SCHEMBL2907824 | 0.83 | MAPT (0.39) | NR1H4KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |