Chloroxine

Chloroxine

SCHEMBL29157288

Oc1c(Cl)cc(Cl)c2cccnc12.Oc1c(I)cc(I)c2cccnc12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.80
MEN1 O00255 5/20 0.80
HTT P42858 5/20 0.80
KMT2A Q03164 5/20 0.80
SMN1; SMN2 Q16637 5/20 0.80
TDP1 Q9NUW8 5/20 0.80
LMNA P02545 5/20 0.80
HSP90AA1 P07900 5/20 0.80
MAPT P10636 5/20 0.80
ALDH1A1 P00352 4/20 0.80
TP53 P04637 3/20 0.80
ALOX15 P16050 3/20 0.80
SLC6A2 P23975 3/20 0.80
MMP14 P50281 3/20 0.80
OPRK1 P41145 3/20 0.80
METAP2 P50579 3/20 0.80
USP2 O75604 2/20 0.80
CYP3A4 P08684 2/20 0.80
HPGD P15428 2/20 0.80
ALOX12 P18054 2/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Clioquinol SCHEMBL3967 0.89 KDM4E (1.00) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL11749381 0.89 KDM4E (1.00) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL30592904 0.89 KDM4E (1.00) KDM4EMEN1HTTKMT2ASMN1; SMN2
SCHEMBL112466 0.89 KDM4E (0.76) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL29370380 0.89 KDM4E (1.00) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL28524321 0.88 KDM4E (0.97) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL18985133 0.88 KDM4E (0.97) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL28529781 0.88 KDM4E (0.97) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL28531298 0.88 KDM4E (0.97) KDM4EMEN1HTTKMT2ASMN1; SMN2
Clioquinol SCHEMBL28198183 0.88 KDM4E (0.97) KDM4EMEN1HTTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117241781-A Loading of alginate microspheres 德克萨斯大学系统董事会 2023-12-15 CN disclosed