Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29157405 | 0.80 | KMT2A (0.40) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A | |
| SCHEMBL1653895 | 0.78 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A | |
| SCHEMBL23851965 | 0.75 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL31588192 | 0.75 | ALDH1A1 (0.58) | SMN1; SMN2MAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL31693952 | 0.74 | MAPT (0.56) | SMN1; SMN2MAPTSERPINE1ALDH1A1MAPK1 | |
| SCHEMBL6541698 | 0.74 | MAPT (0.56) | SMN1; SMN2MAPTSERPINE1ALDH1A1MAPK1 | |
| SCHEMBL7978483 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A | |
| SCHEMBL7981185 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A | |
| SCHEMBL27692447 | 0.73 | TDP1 (0.63) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A | |
| SCHEMBL2064392 | 0.73 | TDP1 (0.63) | SMN1; SMN2MAPTSERPINE1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263943-A | Selective inhibitors of poly (ADP-ribose) polymerase | 轩竹生物科技股份有限公司 | 2023-12-22 | — | — | CN | disclosed |