Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.53 |
| ▸ | RPA1 | P27694 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.49 |
| ▸ | CCKAR | P32238 | 1/20 | 0.48 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2917284 | 0.93 | MGLL (0.63) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2915589 | 0.92 | MGLL (0.63) | MGLLRPA1PTGS2CCKAR | |
| SCHEMBL2916368 | 0.92 | MALT1 (0.55) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2919514 | 0.90 | MGLL (0.50) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2912571 | 0.90 | MGLL (0.52) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2919473 | 0.90 | PTGS2 (0.62) | MGLLPTGS2 | |
| SCHEMBL2909483 | 0.90 | MGLL (0.50) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2915275 | 0.89 | MGLL (0.49) | MGLLRPA1PTGS2CCKARMALT1 | |
| SCHEMBL2915533 | 0.89 | MGLL (0.52) | MGLLRPA1PTGS2CCKARMALT1 | |
| Hydrochloric Acid SCHEMBL2920959 | 0.89 | MGLL (0.51) | MGLLRPA1PTGS2CCKARMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |