Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.36 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | UGCG | Q16739 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158599 | 1.00 | CTSS (0.36) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL23085662 | 1.00 | CTSS (0.36) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL30798694 | 1.00 | CTSS (0.36) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL29546545 | 0.91 | CETP (0.35) | GPR119EGLN2CETPARUGCG | |
| SCHEMBL24370924 | 0.91 | CETP (0.35) | GPR119EGLN2CETPARUGCG | |
| SCHEMBL23085845 | 0.90 | LRRK2 (0.37) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL29158564 | 0.90 | LRRK2 (0.37) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL29158567 | 0.90 | LRRK2 (0.37) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL29470224 | 0.90 | LRRK2 (0.37) | CTSSCTSKGPR119KDM4DNSD2 | |
| SCHEMBL23069404 | 0.90 | LRRK2 (0.36) | UGCGGPR6TLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341133-B | Substituted cyanopyrrolidines having USP30 inhibitor activity | 特殊治疗有限公司 | 2024-02-27 | — | — | CN | disclosed |