Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 2/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353073 | 0.91 | CNR1 (0.54) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL16197705 | 0.90 | CNR1 (0.57) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL29838955 | 0.90 | CYP1A2 (0.57) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL30936703 | 0.88 | CNR1 (0.60) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL2918377 | 0.87 | CNR1 (0.51) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL25197049 | 0.86 | MDM2 (0.62) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| SCHEMBL277784 | 0.83 | CNR1 (0.62) | CYP1A2CNR1CNR2CA1CA2 | |
| SCHEMBL2919412 | 0.83 | ALDH1A1 (0.73) | CYP2C9CYP2C19CYP1A2CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL278149 | 0.82 | CNR1 (0.61) | CYP1A2CNR1CNR2CA1CA2 | |
| SCHEMBL253744 | 0.81 | KDM4E (0.60) | CYP2C9CYP2C19CYP1A2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092205-A1 | INHIBITION OF SHIP1 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-05-02 | — | — | WO | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7358371-B2 | Process for the preparation of 1,5—carboxylic acid derivatives | SANOFI-AVENTIS (FR) | 2008-04-15 | — | — | US | disclosed |
| US-20070099978-A1 | Process for the preparation of 1,5 - carboxylic acid derivatives | SANOFI-AVENTIS (FR) | 2007-05-03 | — | — | US | disclosed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128685-A1 | Pyrazole derivative | PTGS1, PTGS2, PTGER1 | CYP2C9 251/4885CYP2C19 129/4885CYP1A2 176/4885 |
| US-20070099978-A1 | Process for the preparation of 1,5 - carboxylic acid derivatives | CNR1, CNR2, MALT1 | CYP2C9 619/4885CYP2C19 832/4885CYP1A2 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.