Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR3 | P22607 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.48 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28498241 | 0.85 | FGFR3 (0.69) | FGFR3EGFRERBB3FGFR1MAPT | |
| SCHEMBL374616 | 0.77 | FGFR3 (0.82) | FGFR3EGFRERBB3FGFR1 | |
| SCHEMBL28497440 | 0.72 | EGFR (0.60) | FGFR3EGFRERBB3FGFR1L3MBTL1 | |
| SCHEMBL374803 | 0.72 | FGFR3 (0.69) | FGFR3EGFRERBB3FGFR1GFER | |
| SCHEMBL28498357 | 0.71 | EGFR (0.66) | FGFR3EGFRERBB3FGFR1MAPT | |
| SCHEMBL374531 | 0.70 | FGFR3 (0.79) | FGFR3EGFRERBB3FGFR1MAPT | |
| SCHEMBL374370 | 0.69 | FGFR3 (0.82) | FGFR3EGFRERBB3 | |
| SCHEMBL374127 | 0.68 | FGFR3 (0.75) | FGFR3EGFRERBB3MAPTPOLB | |
| SCHEMBL374587 | 0.68 | FGFR3 (1.00) | FGFR3EGFRERBB3FGFR1 | |
| SCHEMBL19427718 | 0.68 | MAPT (0.79) | L3MBTL1MAPTPOLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283130-B | 1- (2, 5-dimethoxy phenyl) -3-substituted urea colon cancer inhibitor and preparation and application thereof | 温州医科大学 | 2023-12-19 | — | — | CN | disclosed |