Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL27699830 | 0.78 | GRM8 (0.55) | SLC7A5HPGDALDH1A1LMNACYP2C9 | |
| Benzophenone SCHEMBL29159318 | 0.76 | SLC7A5 (0.62) | SLC7A5HPGDALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL31323921 | 0.75 | POLB (0.60) | SLC7A5HPGDALDH1A1LMNAKDM4E | |
| Leucine SCHEMBL3362642 | 0.75 | SLC7A5 (0.95) | SLC7A5PTGS1RNPEPSLC1A3SLC1A2 | |
| Leucine SCHEMBL3362636 | 0.75 | SLC7A5 (0.95) | SLC7A5PTGS1RNPEPSLC1A3SLC1A2 | |
| Naphthalene SCHEMBL8050413 | 0.74 | SLC7A5 (0.69) | SLC7A5PTGS1ANPEPRNPEPDNPEP | |
| Naphthalene SCHEMBL8050416 | 0.74 | SLC7A5 (0.69) | SLC7A5PTGS1ANPEPRNPEPDNPEP | |
| Phenylalanine SCHEMBL10945389 | 0.73 | SLC7A5 (0.76) | SLC7A5PTGS1ANPEPRNPEPDNPEP | |
| Dl-Phenylalanine SCHEMBL31087886 | 0.73 | SLC7A5 (0.76) | SLC7A5PTGS1ANPEPRNPEPDNPEP | |
| D-Phenylalanine SCHEMBL10775923 | 0.73 | SLC7A5 (0.76) | SLC7A5PTGS1ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117603042-A | Preparation method and application of ketoleucine salt derivative | 河北天成药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |