Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM8 | O00222 | 1/20 | 0.55 |
| ▸ | GRM6 | O15303 | 1/20 | 0.55 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.55 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.55 |
| ▸ | GSR | P00390 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 1/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.55 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.55 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.55 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Glutamate SCHEMBL6486892 | 0.78 | GRM8 (0.90) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL6574172 | 0.76 | GRM8 (0.95) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL561574 | 0.76 | SLC1A3 (0.64) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Biphenyl SCHEMBL7780462 | 0.75 | SLC1A3 (0.69) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Phenylalanine SCHEMBL4771386 | 0.74 | SLC7A5 (0.76) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Dl-Phenylalanine SCHEMBL22500896 | 0.74 | SLC7A5 (0.76) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL939698 | 0.74 | GRM8 (0.90) | GRM8GRM6GRIN2DGRIN3BGSR | |
| Glutamic Acid SCHEMBL939699 | 0.74 | GRM8 (0.90) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL43222 | 0.74 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR | |
| D-Glutamate SCHEMBL1330566 | 0.74 | GRM8 (1.00) | GRM8GRM6GRIN2DGRIN3BGSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171052-A | Compounds that inhibit KSP kinesin activity | SCHERING CORP (US) | 2008-04-30 | — | — | CN | disclosed |