Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601791 | 0.88 | MCL1 (0.49) | PKMMCL1FFAR1PPARGPPARD | |
| SCHEMBL29159665 | 0.80 | PDK2 (0.41) | LMNAHSD17B10HPGD | |
| SCHEMBL31566186 | 0.80 | PDK2 (0.41) | LMNAHSD17B10HPGD | |
| SCHEMBL19555342 | 0.77 | ALOX15 (0.52) | PKMMCL1FFAR1PPARGPPARD | |
| SCHEMBL6835428 | 0.77 | PTPN7 (0.53) | PKMMCL1FFAR1PPARGPPARD | |
| SCHEMBL3138757 | 0.75 | ALOX15 (0.50) | PKMMCL1FFAR1ALOX15LMNA | |
| SCHEMBL26730009 | 0.74 | HPGD (0.51) | MCL1FFAR1ALOX15LMNATHRB | |
| SCHEMBL7491758 | 0.73 | MCL1 (0.66) | MCL1FFAR1PPARGPPARDALOX15 | |
| SCHEMBL22601788 | 0.73 | MCL1 (0.56) | MCL1ALOX15LMNATHRBTHRA | |
| SCHEMBL22588114 | 0.72 | LDHA (0.47) | MCL1FFAR1PPARGPPARDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580824-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-02-20 | — | — | CN | disclosed |