Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211223 | 0.91 | CHRM4 (0.53) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL24820902 | 0.86 | CHRM4 (0.47) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL5960591 | 0.84 | CHRM4 (0.47) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL17494944 | 0.83 | CHRM4 (0.52) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL1467859 | 0.83 | MEN1 (0.48) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL13229193 | 0.81 | CHRM4 (0.46) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL23063860 | 0.78 | DRD2 (0.52) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL3905057 | 0.78 | ESR2 (0.61) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL11977137 | 0.78 | DRD2 (0.50) | CHRM4DRD2HTR7ESR2NR1H2 | |
| SCHEMBL6297834 | 0.77 | CHRM4 (0.51) | CHRM4DRD2HTR7ESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117580849-A | Steroid compound, pharmaceutical composition and application thereof | 江苏先声药业有限公司 | 2024-02-20 | — | — | CN | disclosed |