Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211223 | 0.89 | CHRM4 (0.53) | CHRM4DRD2HTR7DHODHESR2 | |
| SCHEMBL29159709 | 0.86 | CHRM4 (0.48) | CHRM4DRD2HTR7DHODHESR2 | |
| SCHEMBL11977137 | 0.86 | DRD2 (0.50) | CHRM4DRD2HTR7MPODHODH | |
| SCHEMBL3208941 | 0.83 | DRD2 (0.52) | CHRM4DRD2HTR7MPODHODH | |
| SCHEMBL29888719 | 0.83 | DRD2 (0.52) | CHRM4DRD2HTR7MPODHODH | |
| SCHEMBL27212338 | 0.82 | XIAP (0.47) | DRD2XIAPBIRC2NOTUMNPC1 | |
| SCHEMBL11976686 | 0.81 | DRD2 (0.48) | CHRM4DRD2HTR7MPODHODH | |
| SCHEMBL1467859 | 0.81 | MEN1 (0.48) | CHRM4DRD2HTR7DHODHESR2 | |
| SCHEMBL17494944 | 0.81 | CHRM4 (0.52) | CHRM4DRD2HTR7DHODHESR2 | |
| SCHEMBL3905057 | 0.76 | ESR2 (0.61) | CHRM4DRD2HTR7DHODHESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119156230-A | Ligand-drug conjugates and uses thereof | 江苏先声药业有限公司 | 2024-12-17 | — | — | CN | disclosed |
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | JIANGSU SIMCERE PHARMACEUTICAL CO., LTD. (CN) | 2024-09-19 | — | — | US | disclosed |
| EP-4365183-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | Jiangsu Simcere Pharmaceutical Co., Ltd. (CN) | 2024-05-08 | — | — | EP | disclosed |
| CN-117580849-A | Steroid compound, pharmaceutical composition and application thereof | 江苏先声药业有限公司 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023186072-A1 | LIGAND-DRUG CONJUGATE AND USE THEREOF | 江苏先声药业有限公司 | 2023-10-05 | — | — | WO | disclosed |
| WO-2022268176-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 江苏先声药业有限公司 | 2022-12-29 | — | — | WO | disclosed |
| WO-2022268176-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 江苏先声药业有限公司 | 2022-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240307415-A1 | STEROID COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | NR5A1, HSD17B7, CYP17A1 | CHRM4 4834/4885DRD2 3615/4885HTR7 3184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.