Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28786609 | 0.83 | L3MBTL1 (0.39) | FNTAFNTBS1PR3S1PR4S1PR1 | |
| SCHEMBL28754383 | 0.77 | EGLN2 (0.35) | S1PR3S1PR4S1PR1CTSA | |
| SCHEMBL28754410 | 0.75 | EGLN2 (0.37) | CTSA | |
| SCHEMBL22391829 | 0.73 | PKM (0.34) | FNTAFNTBCTSA | |
| SCHEMBL29159885 | 0.71 | S1PR3 (0.34) | S1PR3S1PR4S1PR1CTSA | |
| SCHEMBL24958707 | 0.68 | GRM5 (0.46) | CYP19A1 | |
| SCHEMBL29098018 | 0.68 | PDE2A (0.39) | CYP11B1CA12CA2CA3CA6 | |
| SCHEMBL30200169 | 0.68 | PDE2A (0.39) | CYP11B1CA12CA2CA3CA6 | |
| SCHEMBL29098016 | 0.68 | PDE2A (0.39) | CYP11B1CA12CA2CA3CA6 | |
| SCHEMBL29098047 | 0.68 | PDE2A (0.39) | CYP11B1CA12CA2CA3CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295729-A | Carboxy-benzimidazole GLP-1R modulating compounds | 吉利德科学公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117279905-A | Carboxy-benzimidazole GLP-1R modulating compounds | 吉利德科学公司 | 2023-12-22 | — | — | CN | disclosed |