SCHEMBL2916010

SCHEMBL2916010

C=CCOc1c(C)cccc1[Si](C)(C)C1C(OC)=Cc2ccccc21

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 0.37
MYB P10242 1/20 0.32
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 2/20 0.30
POLB P06746 1/20 0.30
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
HTR2B P41595 1/20 0.30
ALDH1A1 P00352 1/20 0.30
NPC1 O15118 1/20 0.30
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2921948 0.88 LMNA (0.31) CXCR5MYBMAPTLMNANPSR1
SCHEMBL2919771 0.87 MYB (0.31) MYB
SCHEMBL2921696 0.84 HTR2A (0.38) MAPTLMNAMEN1KMT2AKDM4E
SCHEMBL2924154 0.84 CXCR5 (0.36) CXCR5
SCHEMBL2924942 0.84 MYB (0.32) MYBMEN1KMT2A
SCHEMBL2917037 0.81
SCHEMBL2921361 0.81 MGAM (0.34) HTR2BGAA
SCHEMBL2923357 0.81 MYB (0.32) MYBMEN1KMT2APTGS1PTGS2
SCHEMBL6191676 0.81 CXCR5 (0.39) CXCR5MAPTALDH1A1GAA
SCHEMBL2923359 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1475383-B1 TRANSITION METAL COMPLEXES, LIGANDS, POLYMERIZATION CATALYSTS FOR OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2010-09-08 EP disclosed
US-7241927-B2 Transition metal complexes, ligands, catalysts for olefin polymerization, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-07-10 US disclosed
US-7141690-B2 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-11-28 US disclosed
US-20060111525-A1 Transition metal complexes, ligands, catalysts for olefin polymerization, and process for production of olefin polymers HANAOKA HIDENORI 2006-05-25 US disclosed
US-20050154158-A1 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-14 US disclosed
EP-1475383-A1 TRANSITION METAL COMPLEXES, LIGANDS, POLYMERIZATION CATALYSTS FOR OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS Sumitomo Chemical Company, Limited (JP) 2004-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154158-A1 Transition metal complexes, ligands, polymerization catalysts for olefins, and process for production of olefin polymers PYM1, OR10J3, AP1M1 CXCR5 330/4885MYB 8/4885MAPT 3972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.