SCHEMBL291602

SCHEMBL291602

CNc1ccc(Cc2ccc(NC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
HPGD P15428 4/20 0.52
LMNA P02545 2/20 0.52
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
KDM4E B2RXH2 1/20 0.52
TSHR P16473 4/20 0.50
APP P05067 4/20 0.47
CYP3A4 P08684 3/20 0.43
TDP1 Q9NUW8 2/20 0.43
MAPK1 P28482 1/20 0.43
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
RECQL P46063 2/20 0.42
HSD17B10 Q99714 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
TP53 P04637 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18951277 0.89 MAPT (0.48) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL1108578 0.89 TSHR (0.62) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL922759 0.87 ALDH1A1 (0.67) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL23742242 0.87 TAAR1 (0.50) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL17705702 0.87 ALDH1A1 (0.43) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL3177673 0.85 TSHR (0.61) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL7009496 0.85 ALDH1A1 (0.42) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL13573418 0.83 HPGD (0.52) ALDH1A1HPGDLMNAHTTSMN1; SMN2
SCHEMBL13127241 0.83 SAE1 (0.65) ALDH1A1LMNAKDM4EAPPTDP1
SCHEMBL15342891 0.83 TDP1 (0.48) ALDH1A1HPGDLMNAHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2776 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117659389-A Semi-aromatic polyamide with low water absorption and preparation method thereof 山东广垠新材料有限公司 2024-03-08 CN claimed
CN-116622031-A Synthesis and application of aromatic aqueous polyurethane/acrylic ester composition 万华化学集团股份有限公司 2023-08-22 CN claimed
US-11406964-B2 Heterogeneous catalysts for the synthesis of carbamates COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2022-08-09 US claimed
EP-3625210-B1 SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2021-06-23 EP claimed
US-20210053031-A1 HETEROGENEOUS CATALYSTS FOR THE SYNTHESIS OF CARBAMATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-02-25 US claimed
US-10807084-B2 Silica-based zinc catalysts, their preparation and use in the alkoxycarbonylation of amines COVESTRO DEUTSCHLAND AG (DE) 2020-10-20 US claimed
EP-3717567-A1 A THERMOPLASTIC POLYAMIDE COMPOSITION AND A MANUFACTURING METHOD AND AN APPLICATION THEREOF BASF SE (DE) 2020-10-07 EP claimed
CN-111372998-A Thermoplastic polyamide composition, process for its preparation and its use 巴斯夫欧洲公司 2020-07-03 CN claimed
US-20200147594-A1 SILICA-BASED ZINC CATALYSTS, THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES COVESTRO DEUTSCHLAND AG (DE) 2020-05-14 US claimed
EP-3625210-A1 SILICA-BASED ZINC CATALYSTS. THEIR PREPARATION AND USE IN THE ALKOXYCARBONYLATION OF AMINES Covestro Deutschland AG (DE) 2020-03-25 EP claimed
EP-0573573-A1 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1993-12-15 EP claimed
US-5196587-A Pretreatment with ruthenium hydrogenation catalyst and then with a rhodium catalyst AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-03-23 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
US-5071947-A Polymerization of a bismaleimide and an aromatic secondary diamine in the presence of dicumyl peroxide and imidazole mixed catalyst LUCKY, LTD. (KR) 1991-12-10 US claimed
EP-0166321-B1 HYDROPHOBIC POLYAMIDES BAYER AG (DE) 1990-08-08 EP claimed
US-4616053-A Hydrophobic polyamides BAYER AKTIENGESELLSCHAFT (DE) 1986-10-07 US claimed
EP-0166321-A2 Hydrophobic polyamides BAYER AG (DE) 1986-01-02 EP claimed
US-4267122-A USEFUL AS CORROSION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US claimed
US-4126634-A CORROSION INHIBITORS BASF AKTIENGESELLSCHAFT (DE) 1978-11-21 US claimed
US-4071492-A Polyurethane-urea elastomers based on propylene oxide-tetrahydrofuran copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-01-31 US claimed