Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4264696 | 0.90 | LMNA (0.48) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL291602 | 0.87 | ALDH1A1 (0.52) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL11476899 | 0.87 | CYP3A4 (0.50) | ALDH1A1LMNAHPGDKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL7597445 | 0.85 | LMNA (0.43) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31563712 | 0.85 | CYP3A4 (0.48) | ALDH1A1LMNAHPGDKDM4ETSHR | |
| SCHEMBL486301 | 0.81 | IDO1 (0.59) | ALDH1A1LMNASMN1; SMN2TSHRCYP3A4 | |
| SCHEMBL922759 | 0.81 | ALDH1A1 (0.67) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL17705699 | 0.81 | CYP3A4 (0.67) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4381619 | 0.79 | CYP3A4 (0.56) | ALDH1A1LMNASMN1; SMN2KDM4ETSHR | |
| SCHEMBL18951277 | 0.78 | MAPT (0.48) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439968-B2 | Amine-containing lipidoids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160114042-A1 | AMINE-CONTAINING LIPIDOIDS AND USES THEREOF | ABCB4, PHOSPHO1, SGMS2 | ALDH1A1 872/4885LMNA 683/4885HPGD 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.