Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2907825 | 0.90 | ALDH1A1 (0.34) | MEN1KMT2AL3MBTL1MGLL | |
| SCHEMBL2914123 | 0.90 | MEN1 (0.33) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL2907963 | 0.84 | GLRA3 (0.38) | MEN1KMT2A | |
| SCHEMBL2913600 | 0.82 | NR1H4 (0.40) | MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL2915054 | 0.82 | NR1H4 (0.40) | MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL2913384 | 0.82 | NR1H4 (0.40) | MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL2909795 | 0.81 | NR1H4 (0.39) | MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL2917122 | 0.80 | MAPT (0.42) | MEN1KMT2AL3MBTL1HSD17B10 | |
| SCHEMBL2910598 | 0.80 | NR1H4 (0.56) | — | |
| SCHEMBL2910576 | 0.80 | MEN1 (0.35) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| EP-2203431-A1 | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | Abbott Laboratories (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009039134-A1 | ANTI-INFECTIVE PYRIMIDINES AND USES THEREOF | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |