Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.38 |
| ▸ | GLRB | P48167 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912406 | 0.87 | ALDH1A1 (0.35) | KDM4EALDH1A1CYP1A2CYP2C9TDP1 | |
| SCHEMBL2916134 | 0.84 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL2912963 | 0.84 | ALDH1A1 (0.42) | ALDH1A1MEN1LMNATSHRKMT2A | |
| SCHEMBL2915264 | 0.83 | MAOB (0.37) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL2908073 | 0.79 | NR1H4 (0.47) | MEN1KMT2A | |
| SCHEMBL2913419 | 0.78 | ADORA2A (0.42) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL2913166 | 0.78 | XDH (0.38) | KDM4EALDH1A1HPGDMEN1LMNA | |
| SCHEMBL2907837 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1MEN1LMNAPTGS2 | |
| SCHEMBL2910291 | 0.77 | CNR2 (0.38) | KDM4EALDH1A1MEN1LMNAADRA1A | |
| SCHEMBL2907825 | 0.76 | ALDH1A1 (0.34) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222646-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | Abbott Laboratories (US) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009039127-A1 | URACIL OR THYMINE DERIVATIVE FOR TREATING HEPATITIS C | ABBOTT LABORATORIES (US) | 2009-03-26 | — | — | WO | disclosed |