SCHEMBL29165709

SCHEMBL29165709

O=C1c2ccccc2S(=O)(=O)N1c1cccs1

nearest known ligand 0.51

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
ELANE P08246 3/20 0.49
CTSG P08311 1/20 0.49
CEL P19835 1/20 0.49
CA9 Q16790 13/20 0.49
CA2 P00918 5/20 0.49
CA12 O43570 13/20 0.45
HPGD P15428 1/20 0.43
CA1 P00915 2/20 0.41
CYP2D6 P10635 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30367636 0.74 HPGD (0.58) LMNAELANECTSGCELCA9
SCHEMBL6903338 0.74 HPGD (0.58) LMNAELANECTSGCELCA9
SCHEMBL11098950 0.73 ELANE (0.77) LMNAELANECTSGCELCA9
Hydrogen Sulfide SCHEMBL29165723 0.73 HPGD (0.57) LMNAELANECTSGCELCA9
SCHEMBL11437248 0.70 KMT2A (0.56) ELANECA9CA2CA12CYP2D6
Saccharin Calcium SCHEMBL29394622 0.70 CA9 (0.60) LMNAELANECTSGCELCA9
SCHEMBL31231930 0.70 KMT2A (0.49) CA9CA2CA12HPGDCA1
SCHEMBL606359 0.70 KMT2A (0.49) CA9CA2CA12HPGDCA1
SCHEMBL29151571 0.69 ELANE (0.78) LMNAELANECA9CA2CA12
SCHEMBL9126721 0.69 ELANE (0.54) LMNAELANECTSGCELCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947755-B Synthesis method of biaryl aniline axial chiral derivative 泽升科技(广州)有限公司 2023-05-09 CN disclosed
CN-115947755-A Synthetic method of biarylaniline axial chiral derivative 泽升科技(广州)有限公司 2023-04-11 CN disclosed