SCHEMBL606359

SCHEMBL606359

O=C1c2ccccc2C(=O)N1c1cccs1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.49
ALDH1A1 P00352 4/20 0.49
MEN1 O00255 3/20 0.49
KDM4E B2RXH2 3/20 0.49
HSD17B10 Q99714 2/20 0.49
USP2 O75604 1/20 0.49
HPGD P15428 2/20 0.43
HTT P42858 2/20 0.43
AR P10275 2/20 0.41
GLA P06280 1/20 0.41
BRCA1 P38398 1/20 0.41
POLB P06746 1/20 0.40
CASP1 P29466 1/20 0.39
SCN2A Q99250 2/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31231930 1.00 KMT2A (0.49) KMT2AALDH1A1MEN1KDM4EHSD17B10
SCHEMBL28385189 0.81 KCNH2 (0.37) KMT2AALDH1A1MEN1KDM4EHSD17B10
SCHEMBL21474631 0.75 DPP4 (0.37) KMT2AALDH1A1MEN1KDM4EHPGD
SCHEMBL11591273 0.75 NR1H2 (0.33) AR
SCHEMBL191887 0.74 TLR9 (0.44)
SCHEMBL15571974 0.72 BCAT2 (0.49) KMT2AALDH1A1KDM4EMAPT
SCHEMBL20062962 0.70 TLR9 (0.34) KMT2AALDH1A1MEN1KDM4EHSD17B10
SCHEMBL10766405 0.69 MAPT (0.37) KMT2AALDH1A1MEN1KDM4EHSD17B10
SCHEMBL28581938 0.69 NR1I2 (0.44) KMT2AALDH1A1MEN1KDM4EHSD17B10
SCHEMBL11594002 0.69 MGLL (0.47) ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551023-A Preparation method and application of N-thio-phenyl phthalimide compound 太原理工大学 2024-02-13 CN claimed
EP-1034224-B1 BIOCIDAL POWDER COATING COMPOSITION, ITS PREPARATION AND USE DU PONT (US) 2005-01-05 EP claimed
WO-1999018162-A9 BIOCIDAL POWDER COATING COMPOSITION, ITS PREPARATION AND USE HERBERTS GMBH (DE) 1999-06-03 WO claimed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP claimed
CN-113121563-B Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2022-10-28 CN disclosed
CN-113121563-B Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2022-10-28 CN disclosed
CN-113121563-A Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2021-07-16 CN disclosed
CN-113121563-A Thienophthalimide compound, thiophenethiol and preparation and application thereof 北京化工大学 2021-07-16 CN disclosed
WO-2021137825-A1 ELECTROACTIVE CHEMILUMINESCENT COMPOUNDS FOR DETECTING BLOOD IN FORENSIC SCIENCE ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-07-08 WO disclosed
CN-110143968-B Dithienophenyldiimide derivative and preparation method and application thereof 南京邮电大学 2020-12-01 CN disclosed
US-8114905-B2 Compacted 2,2-dibromo-3-nitrilopropionamide BROMINE COMPOUNDS LIMITED (IL) 2012-02-14 US disclosed
CN-1709870-B Optical-purity N',N'-dibasic prolyl hydrazine compound, and its preparing method and use CHENGDU BIOLOGY INST CHINESE ACADEMY OF SCIENCES 2011-07-06 CN disclosed
EP-1322600-B1 A COMPACTED 2,2-DIBROMO-3-NITRILOPROPIONAMIDE BROMINE COMPOUNDS LTD (IL) 2004-03-03 EP disclosed
EP-1322600-A1 A COMPACTED 2,2-DIBROMO-3-NITRILOPROPIONAMIDE Bromine Compounds Ltd. (IL) 2003-07-02 EP disclosed
WO-2002026699-A1 A COMPACTED 2,2-DIBROMO-3-NITRILOPROPIONAMIDE BROMINE COMPOUNDS LTD. (IL) 2002-04-04 WO disclosed
EP-1034224-A1 BIOCIDAL POWDER COATING COMPOSITION, ITS PREPARATION AND USE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2000-09-13 EP disclosed
WO-1999018162-A9 BIOCIDAL POWDER COATING COMPOSITION, ITS PREPARATION AND USE HERBERTS GMBH (DE) 1999-06-03 WO disclosed
WO-1999018162-A1 BIOCIDAL POWDER COATING COMPOSITION, ITS PREPARATION AND USE E.I. DU PONT DE NEMOURS AND COMPANY, INC. (US) 1999-04-15 WO disclosed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed
EP-0311033-A2 3-Phthalimidothiophenes or their addition products with morpholine, process for their preparation, their use in the preparation of 3-amino-thiophenes and the 3-amino-5-chlorthiopene HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP disclosed