Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | EPOR | P19235 | 2/20 | 0.33 |
| ▸ | KDM4A | O75164 | 11/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 11/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29166024 | 0.87 | KDM4A (0.36) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL30801060 | 0.81 | KDM4A (0.33) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL30476800 | 0.75 | FOLH1 (0.45) | CHRM1EPORALDH1A1 | |
| SCHEMBL4602597 | 0.74 | LTA4H (0.39) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL4602594 | 0.74 | LTA4H (0.39) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| SCHEMBL10938658 | 0.73 | EPOR (0.49) | ZDHHC7EPORCA1CA2 | |
| Hydrochloric Acid SCHEMBL5967458 | 0.72 | LTA4H (0.38) | ZDHHC7KDM4AKDM4CKDM5AKDM7A | |
| SCHEMBL26497527 | 0.72 | ZDHHC7 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRNB2 | |
| Hydrochloric Acid SCHEMBL10770242 | 0.72 | TSHR (0.32) | TSHR | |
| SCHEMBL30476796 | 0.70 | HDAC1 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |