Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 10/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29166024 | 0.95 | KDM4A (0.36) | KDM4AKDM4CFOLH1KDM5AKDM7A | |
| SCHEMBL29166041 | 0.81 | CHRM2 (0.35) | KDM4AKDM4CKDM5AKDM7APHF8 | |
| SCHEMBL30476795 | 0.80 | CHRM1 (0.45) | HTR2AHRH1 | |
| SCHEMBL30957333 | 0.78 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL30476800 | 0.76 | FOLH1 (0.45) | HTR2AHRH1FOLH1 | |
| SCHEMBL20165468 | 0.76 | USP2 (0.31) | — | |
| SCHEMBL14879165 | 0.74 | ALDH1A1 (0.32) | — | |
| SCHEMBL11226698 | 0.72 | ALDH1A1 (0.40) | KDM4AKDM4CHTR2AHRH1KDM5A | |
| SCHEMBL15710764 | 0.71 | HTR2A (0.43) | KDM4AKDM4CHTR2AHRH1KDM5A | |
| SCHEMBL15711311 | 0.69 | HTR2A (0.42) | KDM4AKDM4CHTR2AHRH1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460743-A | Small molecule VE-PTP inhibitors | 曼宁研究公司 | 2024-01-26 | — | — | CN | disclosed |