Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916523 | 0.89 | TAAR1 (0.33) | — | |
| SCHEMBL2921458 | 0.89 | CYP1A2 (0.33) | — | |
| SCHEMBL4482110 | 0.84 | CYP1A2 (0.33) | — | |
| SCHEMBL2231150 | 0.82 | TAAR1 (0.39) | — | |
| SCHEMBL2921114 | 0.81 | SYK (0.32) | SYKAURKBKCNH2 | |
| SCHEMBL881080 | 0.79 | SLC6A2 (0.40) | SYKAURKB | |
| SCHEMBL6233281 | 0.77 | — | — | |
| SCHEMBL782154 | 0.77 | TAAR1 (0.31) | SYKAURKB | |
| SCHEMBL6369928 | 0.77 | TAAR1 (0.31) | SYKAURKB | |
| SCHEMBL6364461 | 0.77 | TAAR1 (0.31) | SYKAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774270-B1 | HEATING FLUID TO ISOMERIZE DIMERS TO THERMODYNAMIC ISOMER; CONTACTING WITH TERTIARY AMINE TO FORM ADDUCT; SEPARATION | 3M INNOVATIVE PROPERTIES COMPANY | 2004-08-10 | — | — | US | claimed |
| CN-111057020-B | Tertiary amine modifier of aliphatic isocyanate, preparation method of tertiary amine modifier and light-stable polyurethane foam | 万华化学集团股份有限公司 | 2021-11-23 | — | — | CN | disclosed |
| CN-111057020-A | Tertiary amine modifier of aliphatic isocyanate, preparation method of tertiary amine modifier and light-stable polyurethane foam | 万华化学集团股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-1591443-B1 | PYRAZOLE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2010-08-25 | — | — | EP | disclosed |
| US-7622471-B2 | Pyrazole derivatives having a pyridazine and pyridine functionality | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2009-11-24 | — | — | US | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080064682-A1 | Pyrazole Derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20070254881-A1 | Pyrazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
| EP-1785418-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-05-16 | — | — | EP | disclosed |
| EP-1762568-A1 | PYRAZOLE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-14 | — | — | EP | disclosed |
| US-20060189591-A1 | Five-membered heterocyclic derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| US-20060128685-A1 | Pyrazole derivative | DAIICHI PHARMACEUTICAL CO., LTD., (JP) | 2006-06-15 | — | — | US | disclosed |
| EP-1636285-A1 | CATALYST COMPOSITION TO GET POLYURETHANE PRODUCT WITH GOOD HYDROLYSIS RESISTANCE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1636284-A1 | FUSIBLE CATALYSTS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1621537-A1 | FIVE-MEMBERED HETEROCYCLIC DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-01 | — | — | EP | disclosed |
| EP-1591443-A1 | PYRAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-11-02 | — | — | EP | disclosed |
| WO-2005000932-A1 | FUSIBLE CATALYSTS AND POLYURETHANE PRODUCTS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004113410-A1 | CATALYST COMPOSITION TO GET POLYURETHANE PRODUCT WITH GOOD HYDROLYSIS RESISTANCE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | SYK 1595/4885AURKB 4321/4885KCNH2 2346/4885 |
| US-20070254881-A1 | Pyrazole Derivative | PTGER1, PTGS1, PTGER2 | SYK 1912/4885AURKB 3808/4885KCNH2 2311/4885 |
| US-20060128685-A1 | Pyrazole derivative | PTGS1, PTGS2, PTGER1 | SYK 929/4885AURKB 4219/4885KCNH2 2509/4885 |
| US-20080064682-A1 | Pyrazole Derivatives | NAT1, AR, CBR3 | SYK 3153/4885AURKB 2255/4885KCNH2 813/4885 |
| US-20060189591-A1 | Five-membered heterocyclic derivative | PTGS1, PTGIS, PTGS2 | SYK 981/4885AURKB 3799/4885KCNH2 2295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.