Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 3/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11848838 | 0.78 | PIK3CD (0.48) | HTR6ADORA3ADORA1TAAR1PIK3CD | |
| SCHEMBL2117735 | 0.76 | CYP2C9 (0.45) | HTR6ADORA3ADORA1TAAR1TSHR | |
| SCHEMBL14688312 | 0.75 | PNP (0.45) | HTR6ADORA3ADORA1TAAR1PIK3CD | |
| SCHEMBL31745005 | 0.75 | ADORA1 (0.54) | HTR6ADORA3ADORA1PIK3CDPIK3CB | |
| SCHEMBL14869709 | 0.74 | KCNH3 (0.58) | HTR6ADORA3ADORA1TSHRLMNA | |
| SCHEMBL14366318 | 0.74 | TSHR (0.46) | HTR6ADORA3ADORA1TAAR1TSHR | |
| SCHEMBL559559 | 0.73 | TAAR1 (0.56) | TAAR1TSHRLMNAADRA1D | |
| SCHEMBL30647945 | 0.73 | ADORA3 (0.52) | HTR6ADORA3ADORA1TAAR1PIK3CD | |
| SCHEMBL15599305 | 0.73 | ADORA1 (0.46) | HTR6ADORA3ADORA1PIK3CDPIK3CB | |
| SCHEMBL20508772 | 0.72 | ADORA1 (0.45) | HTR6ADORA3ADORA1PIK3CDPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624137-A | Triazine skeleton small molecule heparin reversal agent and preparation method and application thereof | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |