Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 3/20 | 0.36 |
| ▸ | CMA1 | P23946 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167254 | 0.84 | MAPT (0.34) | MAPTTDP1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7017667 | 0.81 | PPARG (0.38) | MAPTTDP1LMNA | |
| SCHEMBL29167217 | 0.80 | PLA2G4A (0.35) | CTSGCMA1MAPTTDP1MGLL | |
| SCHEMBL4463193 | 0.76 | GAA (0.40) | MAPTSLC6A3LMNATSHRSMN1; SMN2 | |
| SCHEMBL860935 | 0.73 | SRD5A2 (0.47) | LMNA | |
| SCHEMBL7507457 | 0.72 | CDC7 (0.39) | FFAR4NPY5R | |
| SCHEMBL2470686 | 0.71 | MAPT (0.48) | FFAR4MAPTTDP1NPY5RPDCD1 | |
| SCHEMBL7367610 | 0.70 | FFAR4 (0.41) | FFAR4NPY5RTSHR | |
| SCHEMBL403709 | 0.69 | TNF (0.49) | FFAR4MAPTTDP1NPY5R | |
| SCHEMBL29167160 | 0.69 | FFAR4 (0.43) | FFAR4MGLLNPY5RCHRNA7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082216-A | 3-aryl indole KDM1A/HDACs double-target inhibitor, and preparation method and application thereof | 阜外华中心血管病医院 | 2023-05-09 | — | — | CN | disclosed |