Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 9/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.51 |
| ▸ | WIZ | O95785 | 4/20 | 0.51 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.48 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30875990 | 1.00 | CRBN (0.56) | CRBNIKZF2CSNK1A1WIZDDB1 | |
| SCHEMBL23908367 | 0.88 | CRBN (0.60) | CRBNIKZF2CSNK1A1WIZDDB1 | |
| SCHEMBL28575771 | 0.87 | IKZF2 (0.61) | CRBNIKZF2CSNK1A1WIZDDB1 | |
| SCHEMBL21753143 | 0.85 | CRBN (0.59) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL31554630 | 0.85 | CRBN (0.59) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL32660167 | 0.84 | CRBN (0.59) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL21753199 | 0.84 | CRBN (0.59) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL29167407 | 0.84 | IKZF2 (0.60) | CRBNIKZF2CSNK1A1DDB1GSPT1 | |
| SCHEMBL30930637 | 0.84 | CRBN (0.55) | CRBNIKZF2WIZDDB1 | |
| SCHEMBL29767388 | 0.84 | CRBN (0.55) | CRBNIKZF2WIZDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115626927-B | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |