Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | PTPRB | P23467 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168149 | 1.00 | MEN1 (0.38) | MEN1KMT2AAKT1PTPRBMAPK1 | |
| SCHEMBL29168067 | 0.88 | MAPK1 (0.39) | MEN1KMT2AAKT1PTPRBMAPK1 | |
| SCHEMBL30133692 | 0.88 | MAPK1 (0.39) | MEN1KMT2AAKT1PTPRBMAPK1 | |
| SCHEMBL29168065 | 0.88 | MAPK1 (0.39) | MEN1KMT2AAKT1PTPRBMAPK1 | |
| SCHEMBL29168215 | 0.82 | KMT2A (0.40) | MEN1KMT2AAKT1ALDH1A1RORC | |
| SCHEMBL29168044 | 0.82 | KMT2A (0.40) | MEN1KMT2AAKT1ALDH1A1RORC | |
| SCHEMBL29168047 | 0.82 | KMT2A (0.40) | MEN1KMT2AAKT1ALDH1A1RORC | |
| SCHEMBL30133680 | 0.80 | LMNA (0.38) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL29168190 | 0.80 | LMNA (0.38) | MEN1KMT2AMAPK1ALDH1A1MAPT | |
| SCHEMBL29168188 | 0.80 | LMNA (0.38) | MEN1KMT2AMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |