Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | PYGM | P11217 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168198 | 1.00 | LMNA (0.36) | LMNAMAP3K14NPC1RAB9AMEN1 | |
| SCHEMBL29168232 | 0.83 | SMN1; SMN2 (0.36) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL29168179 | 0.81 | KDM4E (0.39) | LMNAMEN1KMT2APYGLPYGM | |
| SCHEMBL29168176 | 0.81 | KDM4E (0.39) | LMNAMEN1KMT2APYGLPYGM | |
| SCHEMBL29168293 | 0.80 | SLC6A2 (0.36) | RAB9AMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29168291 | 0.80 | SLC6A2 (0.36) | RAB9AMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL29168161 | 0.78 | — | — | |
| SCHEMBL29168159 | 0.78 | — | — | |
| SCHEMBL29168183 | 0.75 | PPARG (0.38) | LMNAMAP3K14NPC1RAB9APPARG | |
| SCHEMBL29168184 | 0.75 | PPARG (0.38) | LMNAMAP3K14NPC1RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |