Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168176 | 1.00 | KDM4E (0.39) | KDM4EPNMTKMT2AMEN1LMNA | |
| SCHEMBL29168197 | 0.81 | LMNA (0.36) | KMT2AMEN1LMNAKCNJ5KCNJ3 | |
| SCHEMBL29168198 | 0.81 | LMNA (0.36) | KMT2AMEN1LMNAKCNJ5KCNJ3 | |
| SCHEMBL29168345 | 0.80 | PNMT (0.48) | KDM4EPNMTLMNASMN1; SMN2HDAC8 | |
| SCHEMBL30818206 | 0.80 | PNMT (0.48) | KDM4EPNMTLMNASMN1; SMN2HDAC8 | |
| SCHEMBL29168347 | 0.80 | PNMT (0.48) | KDM4EPNMTLMNASMN1; SMN2HDAC8 | |
| SCHEMBL29168161 | 0.77 | — | — | |
| SCHEMBL29168159 | 0.77 | — | — | |
| SCHEMBL29168316 | 0.75 | PNMT (0.42) | KDM4EPNMTKMT2AHTR3EHTR3B | |
| SCHEMBL29168317 | 0.75 | PNMT (0.42) | KDM4EPNMTKMT2AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529476-A | Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments | 亚飞络思制药公司 | 2024-02-06 | — | — | CN | disclosed |