Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29168383 | 0.91 | KDM4E (0.30) | GAAKDM4EALDH1A1HPGDMAPT | |
| SCHEMBL27186130 | 0.84 | SOS1 (0.39) | — | |
| SCHEMBL27186125 | 0.84 | SOS1 (0.39) | — | |
| SCHEMBL29168348 | 0.74 | P2RX7 (0.34) | IL1BP2RX7KDM4EALDH1A1HPGD | |
| SCHEMBL29844254 | 0.74 | KRAS (0.40) | — | |
| SCHEMBL27186348 | 0.74 | KRAS (0.38) | ALDH1A1 | |
| SCHEMBL27186352 | 0.74 | KRAS (0.38) | ALDH1A1 | |
| SCHEMBL27186885 | 0.74 | KRAS (0.40) | IL1BP2RX7 | |
| SCHEMBL27186887 | 0.74 | KRAS (0.40) | IL1BP2RX7 | |
| SCHEMBL29168387 | 0.74 | RXFP1 (0.33) | GAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651701-A | Novel substituted bicyclic aza heterocycles as SOS1 inhibitors | 唯久生物技术(苏州)有限公司 | 2024-03-05 | — | — | CN | disclosed |