Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 12/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29169000 | 1.00 | PARP1 (0.50) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL31381945 | 0.85 | TIPARP (0.41) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL29169128 | 0.84 | GPR119 (0.50) | PARP1TIPARPLMNASMN1; SMN2TNKS | |
| SCHEMBL29168944 | 0.84 | GPR119 (0.50) | PARP1TIPARPLMNASMN1; SMN2TNKS | |
| SCHEMBL29168949 | 0.84 | GPR119 (0.50) | PARP1TIPARPLMNASMN1; SMN2TNKS | |
| SCHEMBL27233726 | 0.84 | IDO1 (0.51) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL30479858 | 0.81 | PARP1 (0.57) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL31381942 | 0.80 | LMNA (0.50) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL30479877 | 0.80 | TIPARP (0.51) | PARP1TIPARPCHRM2CHRM1LMNA | |
| SCHEMBL26126743 | 0.79 | KDM4E (0.49) | PARP1TIPARPCHRM2CHRM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377665-A | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-01-09 | — | — | CN | disclosed |